Semen Citri Reticulatae
Citrus limonoids are responsible for the bitter taste in citrus
fruits. The most prevalent limonoids are limonin and nomilin. They
are present in the rutaceous plants that include lemon, lime,
orange and grapefruits. An important characteristic of this class
of compound is a substituted furan moiety.
It has been determined by animal studies that citrus limonoids and
derivatives have certain biological activities that may be used as
chemopreventive agents for cancer.