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Articaine Hydrochloride Local Anesthesia Drugs For Pain Reliever 23964-57-0

Categories Local Anesthesia Drugs
Brand Name: Hongkong SaiChuang
Model Number: 23964-57-0
Certification: ISO9001
Place of Origin: China
MOQ: 10g
Price: negotiable USD
Payment Terms: D/P, L/C, D/A, D/P, T/T, Western Union
Supply Ability: 10000KG/Month
Packaging Details: as requested
Name: Articaine hydrochloride
CAS: 23964-57-0
MF: C13H20N2O3S.ClH
MW: 320.839
Purity: 99%
Origin: China
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    Articaine Hydrochloride Local Anesthesia Drugs For Pain Reliever 23964-57-0

    Articaine hydrochloride Local Anaesthetic For Pain Reliever 23964-57-0

    Product Description

    Product Name:Articaine hydrochloride
    CAS: 23964-57-0
    MF: C13H20N2O3S.ClH
    MW: 320.839
    EINECS: 245-957-7
    Appearance: White crystalline powder

    Description

    articaine is a dental local anesthetic. it is the most widely used local anesthetic in a number of european countries[2] and is available in many countries around the world


    articaine hydrochloride,articaine is an intermediate-potency, short-acting amide local anesthetic with a fast metabolism due to an ester group in its structure. it is effective with local infiltration or peripheral nerve block in dentistry, when administered as a spinal, epidural, ocular, or regional nerve block, or when injected intravenously for regional anesthesia.

    articaine hydrochloride, in comparative trials, its clinical effects were not generally significantly different from those of other short-acting local anesthetics like lidocaine, prilocaine, and chloroprocaine, and there is no conclusive evidence demonstrating above-average neurotoxicity. articaine proved to be suitable and safe for procedures requiring a short duration of action in which a fast onset of anesthesia is desired, eg, dental procedures and ambulatory spinal anesthesia, in normal and in special populations.


    Applications

    • Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor .
      The combination of articaine can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.
    • articaine hydrochloride, articaine blocks nerve conduction by reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, similar to other local anesthetics. binding of articaine to the sodium channel reduces sodium influx so that the threshold potential will not be reached and impulse conduction stops. the blocking action of articaine on the sodium channel is state dependent: it has the highest affinity for the open state, an intermediate affinity for the inactivated state, and the lowest affinity for the resting state.
    • articaine hydrochloride, the degree of neuronal block is affected by the diameter of the nerve. larger-diameter fibers (touch/pressure/ motor) require higher concentrations of local anesthetic compared with small myelinated fibers (pain afferents).articaine is lipid soluble, highly protein-bound (94%), and has a dissociation constant (pka) of 7.8. articaine is an intermediate-potency, short-acting local anesthetic with a fast onset of action.

    Specifications

    product namearticaine hydrochloride
    cas23964-57-0outer packing25kg
    production date2016/09/27shelf life2018/09/26
    standard adoptedep 7
    items testedspecificationresult
    descriptionwhite or almost white crystalline powderwhite crystalline powder
    solubilityfreely soluble in water and in alcoholcomplies
    identificationa,b,c,dcomplies
    ph4.2-5.24.90
    appearance of solutionsolution should be clearcomplies
    related substanceimpurity a ≤0.2%; any other impurity ≤0.1%; total of other impurities ≤0.5%
    not detected; 0.08%; 0.26%
    heavy metals≤5ppm<5ppm
    loss on drying< 0.5%0.09%
    residue on ignition≤0.1%0.09%
    organic residuecompliescomplies
    assay98.5%-101.0%99.60%
    conclusionqualified

    How to start orders or make payments
    A:You can send our your Purchase order(if your company has), or just
    send a simple confirmation by email or by Trade Manager, and we will send
    you Proforma Invoice with our bank details for your confirmation, then you
    can make payment accordingly.
    Q: How to confirm the Product Quality before placing orders
    A:You can get free samples for some products,you only need to pay the shipping
    cost or arrange a courier to us and take the samples. You can send us your
    product specifications and requests,we will manufacture the products according
    to your requests.
    Q: What’s your MOQ
    A:For the high value product, our MOQ starts from 1g and generally starts
    from 1kgs. For other low price product, our MOQ starts from 10kg and 100kg.
    Q: Is there a discount
    A: Yes, for larger quantity, we alway support with better price.
    Q:How do you treat quality complaint
    First of all, our quality control will reduce the quality problem to near zero.
    If there is a quality problem caused by us, we will send you free goods for
    replacement or refund your loss.
    Q:How to contact us
    A:You can choose your interested products and send inquiry to us.You can
    dial our telephone directly, you will get our reply.
    Our Superiority

    Quality

    our products meet msds safe standard and we have iso and other certificate so yan can get high quality products from our company.


    Packing

    we can do according to the customers' request.


    Delivery

    We can pack your powders within 12 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.

    Payment


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