HGH 176-191 HGH Peptide Growth Hormone Releasing Factor 66004-57-7
We can supply HGH Fragment 176-191, 2 mg/vial.
Reduces the most stubborn abdominal fat.
- Increases muscle mass.
- Increases IGF-1 levels, in an effective manner, thus making this
a peptide that burns fat and exhibits anabolic function.
- Increases energy expenditure.
- Improves lipid profiles and lipolytic activity.
- Does not negatively impact blood glucose level, nor does cell
proliferation occur, like Human Growth Hormone.
- Extremely potent and effective fat burner.
This peptide comes in 2mg aliquots or 5mg/vial, regardless of the
FOR A DETAILED ANALYSIS PLEASE SEE THE BELOW ARTICE AND VIEW THE
The (HGH fragment 176-191) is a stabilized analogue of the growth
hormone-releasing factor (GRF) that induces growth hormone (GH) in
a specific and physiological manner. To date studies suggest that
(HGH fragment 176-191) has several beneficial features: it reduces
abdominal fat (in particular visceral fat), without compromising
glycemic control (blood glucose), it increases muscle mass and
improves the lipid profile. These characteristics make it an ideal
candidate for the treatment of excess abdominal fat, an important
aspect of HIV-associated lipodystrophy.
At a dosage of 500mcg the (HGH fragment 176-191) was shown to
increase lipolytic activity in adipose tissue. In other words this
fragment potently burns body fat, especially stubborn adipose body
fat, and it does so potently! Of significance, is that the fragment
has no negative impact on insulin sensitivity, a stark contrast
from its Human Growth Hormone counterpart.(Ng FM, Sun J,Sharma L,
Libinaka R, Jiang WJ, and Gianello R 2000).
Not only does the (HGH fragment 176-191) not interfere with the
body’s natural insulin regulation as Human Growth Hormone can, the
(HGH fragment 176-191) does not result in cellular proliferation as
Human Growth Hormone does. The fragment is similar to Human Growth
Hormone, hence the shared amino acid sequence, however, the (HGH
fragment 176-191) does not induce hyperglycaemia or reduce insulin
The (HGH fragment 176-191) does not compete for the hGH receptor
and nor does it induce cell proliferation, unlike Human Growth
Hormone. (Wu Z, Ng FM. 1993). Thusly, this is a very beneficial
peptide in terms of burning fat, without unwanted and undesirable
side effects. Of particular note is the fragments ability to
increase IGF-1 levels which translate into the fragments ability to
give collateral anti-aging and anabolic effects along with its
ability to induce lipplytic (fat burning) activity.
In yet another study, the (HGH fragment 176-191) exhibits the
ability to burn through adipose tissue by increasing lipolytic
activity (the breakdown of fat) , in the most stubborn body fat
(adipose tissue) while increasing energy expenditure and glucose
and fat oxidation in ob/ob mice treated with (HGH fragment
176-191). In addition, (HGH fragment 176-191) increased in vitro
lipolytic activity and decreased lipogenic activity in isolated
adipose tissue from obese rodents and humans.(Heffernan MA, Jiang
WJ, Thorburn AW, Ng FM. 2000).
Thusly, the (HGH fragment 176-191) exhibits the ability to burn
through stubborn adipose tissue, while increasing energy
expenditure, muscle mass, and fat oxidation. All studies have
pointed to the fact that the fragment is an effective treatment for
obesity and fat loss, and much safer than its Human Growth Hormone
- 500mcg-2mg every day
- REFRGIRATE UPON RECEIPT.
KEEP REFRIGERATED AFTER RECONSTITUTION ALLOW 24 HOURS FOR THE
PEPTIDE TO SETTLE BEFORE BEGINNING YOUR RESEARCH.
More information about Hgh Fragment (176-191)
Growth Hormone peptide fragment 176-191, also known as HGH Frag
176-191, is a modified form of amino acids 176-191 of the GH
polypeptide. Investigators at Monash University discovered that the
fat-reducing effects of GH appear to be controlled by a small
region near one end of the Growth Hormone molecule. This region,
which consists of amino acids 176-191, is less than 10% of the
total size of the GH molecule and appears to have no effect on
growth or insulin resistance.
It works by mimicking the way natural Growth Hormone regulates fat
metabolism but without the adverse effects on blood sugar or growth
that is seen with unmodified Growth Hormone. Like Growth Hormone,
the hgH fragment 176-191 stimulates lipolysis (the breakdown or
destruction of fat) and inhibits lipogenesis (the transformation of
nonfat food materials into body fat) both in laboratory testing and
in animals and humans.
Laboratory Tests and Fat Loss
In laboratory tests on fat cells from rodents, pigs, dogs, and
humans, the hgH fragment released fat specifically from obese fat
cells but not from lean ones, reduced new fat accumulation in all
fat cells, enhanced the burning of fat. In rodents (rats and mice),
hgH fragment reduced body fat in obese animals but, enhanced fat
burning without changing food consumption or inducing growth (as it
does not increase IGF levels) or any other unwanted Growth Hormone
effect. Research dosages of 500mcg of the hgH fragment 176-191
daily for 30 days did show a reduction of body fat in the mid
abdominal area in both obese, over-weight, and average built
Fragment 176-191 as an Active HGH Truncated Peptide
hgH fragment 176-191 is an analog of the growth hormone-releasing
factor (GRF) which signals the effects of growth hormone. It is a
15-mer peptide residue of the C-terminus of HGH to which tyrosine
is added at the N-terminal end. This synthetically produced hormone
is very common to weightlifters and bodybuilders because of a
number of physical benefits. Studies claimed that it actually acts
on the reduction of excessive adipose tissues such as those in the
abdominal area, increase in muscle mass, and enhances the lipid
content of the body.
These segments of the synthetic peptide hgH 176-191 have been
investigated for their in vivo effects in laboratory mice musculus.
Research results have shown that hgH 176-191 have resulted to a
short-period increase in blood glucose and a more sustained
increase in plasma insulin, together with other fragments such as
172-191, 177-191 and 178-191. In addition, the researchers have
suggested that functionality of the peptide depends not only in the
informational sequence but should also have the correct physical
configuration (Ng and Borstein 1978).
Also, this fragment, being a region of high accessibility to
proteases and also rich in proline, have been demonstrated to
affect the conformational change in the cytoplasmic domain of the
band 3 of erythrocyte membrane protein by serving as the hinge for
the pivoting of the two subdomains. This then suggest that such
residue is significant in conformational changes be serving as
sites for peripheral protein binding in some body cells (Low et al.
In another study of Ng et al. (2000) on animal subjects, they found
out that a 500mcg dosage of the said hormone increased the
lipolytic activity in adipose tissues without having negative
influence in the blood glucose level. Furthermore, though it
behaves like a human growth hormone (hgH), it does not causes
hyperglycemia because it does not compete with hgH receptors (Wu et
al. 1993). Because of such effects, researchers have suggested that
it might be used for the elimination of excess abdominal fat which
is a significant aspect of HIV-associated lipodystrophy.
The (hgH fragment 176-191) exhibits the ability to burn through
stubborn adipose tissue, while increasing energy expenditure,
muscle mass, and fat oxidation. All studies have pointed to the
fact that the fragment is an effective treatment for obesity and
fat loss, and much safer than its Human Growth Hormone counterpart.
(Please NOTE: It is normal for FRAGMENT (176-191) to mix cloudy
after reconstitution with bacteriostatic water.)